Zero Mile Marathon is named after Zero Milestone of Nagpur, which is the geographical center of India. This milestone was used by the British to measure all other distances within the Indian sub-continent.

There is a sandstone pillar and four horses beside Zero Milestone. Four horses denote four cardinal directions. The passion for cartography by the British led to many cities having zero stones. However, Zero Milestone of Nagpur is unique because it quite literally indicates the center of India. The major National Highways (NH7 from Varanasi to Kanyakumari along with NH6 from Mumbai-Sambalpur-Calcutta cross through the Nagpur City. In addition to these, the Grand Trunk Route from Mumbai-Howrah, Howrah-Chennai, Chennai-Delhi railway lines pass through the city.